For the chemotherapy drugs to get inside the cells, where they can do their job, requires a very high doses of these drugs. If the dose is not high enough then the drug can not force itself across the membranes of cancer cells. But the drawback of this method is the very serious dose-related side effects. The chemotherapy drugs can´t tell the difference between normal cells and cancer cells, so it kills both type of cells. There is a very simple but very effective method to avoid the side effects of chemotherapy drugs. In this article I will tell you more about it.
With the recent advances it is possible to avoid the side effects of chemotherapy drugs dramatically. And also increasing the effectiveness of chemotherapy as well. The key to make the drugs more effective is a strategy called insulin potentiation therapy (IPT). It is a non-diabetic use of the insulin hormone to increase the delivery and effectiveness of standard medications dramatically. This strategy can help the medications act like super drugs, with better results for many millions of patients worldwide.
Insulin is a very powerful hormone and is secreted by the pancreas in healthy people. It is also used to treat diabetes. Insulin[ job is to deliver glucose across cell membranes into cells. All the cells in the human body have receptors on the surface of the cell membrane that communicate to insulin. There can be one hundred to one hundred thousand of receptors per cell.
It is interesting that different studies report that cancer cells actually produce and secrete their own insulin. And cancer cells have ten times more insulin receptors per cell than any of the normal cells in the body. There is a big difference between normal cells and cancer cells and that is very important. It means that the effect of administered insulin will be ten times greater on cancer cells than on normal cells because cancer cells have ten times more insulin receptors.
An effective dose intensity of chemotherapy drugs combined with actions of insulin in IPT is able to be delivered selectively into the cancer cells sparing normal tissue. That can be achieved using greatly reduced doses of the drugs, eliminating the side effects of high doses.
In insulin potentiation therapy insulin administration has an effect to make blood glucose to go down. It is also called hypoglycemia. Hypoglycemia is an side effect of insulin. It is effectively and rapidly controllable with intravenous glucose infusions at an appropriate time, according to the protocol of IPT.
If cancer cells want to grow and divide then they need sugar (glucose). The insulin brings down the levels of blood sugar and when it reaches it[ lowest then the cancer cell is desperate for glucose. Extra amounts of insulin receptors on the cells of the cancer means they will receive many times the amount of glucose/chemo as the normal cell. It is an effective way to concentrate the action in the cancer cells and not killing normal cells.
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